Copyright © 1996, 1997, 2001 by
Galen Daryl Knight and VitaleTherapeutics, Inc.
ß-aletheine (below left) is the reduced or thiol form of the disulfide,
ß-alethine. Although far more potent than other comparable immune
stimulants, such as levamisole,
is considerably less potent than vitalethine. The striking increase in
the potency of ß-alethine upon addition of the carboxy groups to
its free amine moieties to form vitalethine indicates that this process
and its reversal are important regulatory events for biological systems.
The thiol, vitaletheine, is shown below right for comparison.